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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620259
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Eif4ebp1
Name: eukaryotic translation initiation factor 4E binding protein 1
Acc ID: CHEBI:15343
Term: acetaldehyde
Definition: The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
Chemical ID: MESH:D000079
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Eif4ebp1decreases phosphorylationISOEIF4EBP1 (Homo sapiens)6480464CTDAcetaldehyde results in decreased phosphorylation of EIF4EBP1 proteinPMID:16962100
Eif4ebp1multiple interactionsISOEIF4EBP1 (Homo sapiens)6480464CTDSirolimus promotes the reaction [Acetaldehyde results in decreased phosphorylation of EIF4EBP1 protein]PMID:16962100
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