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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1351472
Species: Homo sapiens
RGD Object: Gene
Symbol: ADIPOQ
Name: adiponectin, C1Q and collagen domain containing
Acc ID: CHEBI:15343
Term: acetaldehyde
Definition: The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
Chemical ID: MESH:D000079
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ADIPOQmultiple interactionsEXP 6480464CTDADIPOQ protein inhibits the reaction [Acetaldehyde results in decreased expression of BCL2 mRNA]; ADIPOQ protein inhibits the reaction [Acetaldehyde results in increased activity of CASP3 protein]; ADIPOQ protein inhibits the reaction [Acetaldehyde results in increased expression of BAX mRNA]PMID:16814256
ADIPOQincreases expressionISOAdipoq (Mus musculus)6480464CTDAcetaldehyde results in increased expression of ADIPOQ mRNA; Acetaldehyde results in increased expression of ADIPOQ proteinPMID:17949463
ADIPOQmultiple interactionsISOAdipoq (Mus musculus)6480464CTDAcetaldehyde promotes the reaction [ADIPOQ protein results in decreased expression of COL1A1 mRNA]; LEP protein affects the reaction [Acetaldehyde results in increased expression of ADIPOQ protein]PMID:17949463
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