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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 727889
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rela
Name: RELA proto-oncogene, NF-kB subunit
Acc ID: CHEBI:15342
Term: acenaphthoquinone
Definition: An orthoquinone that is the 1,2-dioxo derivative of acenaphthene.
Chemical ID: MESH:C023722
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Relaincreases expressionISORGD:13527616480464CTDacenaphthenequinone results in increased expression of RELA proteinPMID:17925309
Relamultiple interactionsISORGD:13527616480464CTD2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone inhibits the reaction [acenaphthenequinone results in increased expression of RELA protein]; acenaphthenequinone affects the localization of and results in increased expression of RELA protein; Acetylcysteine inhibits the reaction [acenaphthenequinone results in increased expression of RELA protein]PMID:17082565 PMID:17925309
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