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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2081
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Akt1
Name: AKT serine/threonine kinase 1
Acc ID: CHEBI:149906
Term: Tanshinone I
Definition: null
Chemical ID: MESH:C021751
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akt1increases phosphorylationEXP 6480464CTDtanshinone results in increased phosphorylation of AKT1 proteinPMID:34655285
Akt1multiple interactionsEXP 6480464CTDFulvestrant inhibits the reaction [tanshinone inhibits the reaction [IGF2 protein mutant form results in decreased phosphorylation of AKT1 protein]]; tanshinone inhibits the reaction [IGF2 protein mutant form results in decreased phosphorylation of AKT1 protein]PMID:34655285
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