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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1593476
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptx3
Name: pentraxin 3
Acc ID: CHEBI:149906
Term: Tanshinone I
Definition: null
Chemical ID: MESH:C021751
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptx3decreases expressionISOPTX3 (Homo sapiens)6480464CTDtanshinone results in decreased expression of PTX3 mRNAPMID:30268796
Ptx3decreases secretionISOPTX3 (Homo sapiens)6480464CTDtanshinone results in decreased secretion of PTX3 proteinPMID:30268796
Ptx3multiple interactionsISOPTX3 (Homo sapiens)6480464CTDtanshinone inhibits the reaction [TNF protein results in increased expression of PTX3 mRNA]; tanshinone inhibits the reaction [TNF protein results in increased secretion of PTX3 protein]PMID:30268796
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