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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2755
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gstm1
Name: glutathione S-transferase mu 1
Acc ID: CHEBI:149463
Term: 2-phenylpropanal
Definition: A member of the class of phenylacetaldehydes that is phenylacetaldehyde in which a hydrogen alpha to the aldehyde carbonyl group has been replaced by a methyl group. The major species at pH 7.3.
Chemical ID: MESH:C013026
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gstm1decreases activityISOGSTM1 (Homo sapiens)6480464CTDGSTM1 protein results in decreased activity of hydratropic aldehyde; hydratropic aldehyde results in decreased activity of GSTM1 proteinPMID:11368548
Gstm1multiple interactionsISOGSTM1 (Homo sapiens)6480464CTDGSTM1 protein affects the metabolism of [hydratropic aldehyde co-treated with Glutathione]PMID:11368548
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