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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 727838
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ube2v2
Name: ubiquitin conjugating enzyme E2 V2
Acc ID: CHEBI:147302
Term: CGP-42112A
Definition: A hexapeptide consisting of L-tyrosine, L-lysine, L-histidine, L-proline and L-isoleucine amino acid residues coupled in sequence and in which the amino group of the L-tyrosyl residue is substituted by a (pyridin-3-ylcarbonyl)nitrilo group and in which the L-lysyl side chain amino group is substituted by a {N(2)-[(benzyloxy)carbonyl]-L-arginyl}nitrilo group. It is a potent angiotensin II receptor type 2 (AT2 receptor) agonist.
Chemical ID: MESH:C060894
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ube2v2increases expressionEXP 6480464CTDCGP 42112A results in increased expression of UBE2V2 mRNA; CGP 42112A results in increased expression of UBE2V2 proteinPMID:17068200
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