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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311873
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Orai1
Name: ORAI calcium release-activated calcium modulator 1
Acc ID: CHEBI:145121
Term: SKF-96365 hydrochloride
Definition: The hydrochloride salt of SKF-96365. It is a TRP channel blocker.
Chemical ID: MESH:C063159
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Orai1multiple interactionsEXP 6480464CTD1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of ORAI1 protein]PMID:32895711
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