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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737039
Species: Homo sapiens
RGD Object: Gene
Symbol: CDKN2A
Name: cyclin dependent kinase inhibitor 2A
Acc ID: CHEBI:144804
Term: nickel subsulfide
Definition: A nickel coordination entity with formula Ni3S2. Used in the manufacture of lithium batteries.
Chemical ID: MESH:C017557
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CDKN2Adecreases expressionISOCdkn2a (Rattus norvegicus)6480464CTDnickel subsulfide results in decreased expression of CDKN2A mRNAPMID:21565688
CDKN2Aincreases methylationISOCdkn2a (Rattus norvegicus)6480464CTDnickel subsulfide results in increased methylation of CDKN2A genePMID:21565688
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