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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10473
Species: Mus musculus
RGD Object: Gene
Symbol: Nqo1
Name: NAD(P)H dehydrogenase, quinone 1
Acc ID: CHEBI:144421
Term: iron(III) citrate
Definition: An iron chelate resulting from the combination of iron(3+) and citrate(3-).
Chemical ID: MESH:C025314
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nqo1increases expressionISONQO1 (Homo sapiens)6480464CTDferric citrate results in increased expression of NQO1 mRNA; ferric citrate results in increased expression of NQO1 proteinPMID:29959986
Nqo1multiple interactionsISONQO1 (Homo sapiens)6480464CTDtrigonelline inhibits the reaction [ferric citrate results in increased expression of NQO1 protein]PMID:29959986
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