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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736022
Species: Mus musculus
RGD Object: Gene
Symbol: App
Name: amyloid beta precursor protein
Acc ID: CHEBI:144353
Term: diethyldithiocarbamic acid
Definition: A member of the class of dithiocarbamic acids that is diethylcarbamic acid in which both of the oxygens are replaced by sulfur.
Chemical ID: MESH:D004050
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Appmultiple interactionsISOAPP (Homo sapiens)6480464CTDDitiocarb inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of APP mRNA]; Ditiocarb inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of APP protein]PMID:28242320
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