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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619831
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fas
Name: Fas cell surface death receptor
Acc ID: CHEBI:142921
Term: 3-phenylprop-2-enal
Definition: A member of the class of cinnamaldehydes that is prop-2-enal in which a hydrogen at position 3 has been replaced by a phenyl group. The configuration of the double bond is not specified; the name 'cinnamaldehyde' is widely used to refer to the E (trans) isomer.
Chemical ID: MESH:C012843
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fasdecreases expressionISOFas (Mus musculus)6480464CTDcinnamaldehyde results in decreased expression of FAS mRNAPMID:21401097
Fasmultiple interactionsISOFas (Mus musculus)6480464CTDdorsomorphin inhibits the reaction [cinnamaldehyde results in decreased expression of FAS mRNA]PMID:21401097
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