GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | TNF | increases expression | EXP | | 6480464 | CTD | cinnamaldehyde results in increased expression of TNF mRNA | PMID:20385217 | TNF | multiple interactions | EXP | | 6480464 | CTD | [cinnamaldehyde results in increased activity of GLRX protein] inhibits the reaction [TNF protein affects the localization of RELA protein]; [cinnamaldehyde results in increased activity of GLRX protein] inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; [cinnamaldehyde results in increased activity of NFE2L2 protein] inhibits the reaction [TNF protein affects the localization of RELA protein]; [cinnamaldehyde results in increased activity of NFE2L2 protein] inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; Buthionine Sulfoximine inhibits the reaction [cinnamaldehyde inhibits the reaction [TNF protein affects the localization of RELA protein]]; Buthionine Sulfoximine inhibits the reaction [cinnamaldehyde inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]; cinnamaldehyde inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; cinnamaldehyde inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]; cinnamaldehyde inhibits the reaction [TNF protein affects the localization of RELA protein]; cinnamaldehyde inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] | PMID:17868967 PMID:20351055 PMID:21807015 | TNF | multiple interactions | ISO | Tnf (Mus musculus) | 6480464 | CTD | cinnamaldehyde inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]; cinnamaldehyde inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; cinnamaldehyde inhibits the reaction [lipoteichoic acid results in increased secretion of TNF protein] | PMID:17868967 PMID:20467561 | TNF | multiple interactions | ISO | Tnf (Rattus norvegicus) | 6480464 | CTD | cinnamaldehyde inhibits the reaction [Testosterone results in increased expression of TNF protein]; cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein] | PMID:32628957 PMID:33522063 | | ||||||||||||||||||||||
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