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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70975
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk12
Name: mitogen-activated protein kinase 12
Acc ID: CHEBI:141969
Term: tipifarnib
Definition: A quinolone that is 1-methylquinolin-2-one which carries a 3-chlorophenyl and an amino(4-chlorophenyl)(1-methyl-imidazol-5-yl)methyl groups at the 4 and 6 positions, respectively (the R-isomer).
Chemical ID: MESH:C402769
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk12increases expressionEXP 6480464CTDtipifarnib results in increased expression of MAPK12 mRNAPMID:16403772
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