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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732555
Species: Homo sapiens
RGD Object: Gene
Symbol: GJB1
Name: gap junction protein beta 1
Acc ID: CHEBI:141568
Term: N-ethyl-N-(2-hydroxyethyl)nitrosamine
Definition: A nitrosamine that is N-nitrosodiethylamine in which one of the ethyl froups has been replaced by a 2-hydroxyethyl group. It is used to induce renal and liver tumours in rodents.
Chemical ID: MESH:C023845
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GJB1decreases expressionISOGjb1 (Rattus norvegicus)6480464CTDN-ethyl-N-hydroxyethylnitrosamine results in decreased expression of GJB1 mRNAPMID:2559087
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