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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69218
Species: Mus musculus
RGD Object: Gene
Symbol: Aldh2
Name: aldehyde dehydrogenase 2, mitochondrial
Acc ID: CHEBI:141564
Term: tert-butyl ethyl ether
Definition: An ether having ethyl and tert-butyl as the two alkyl components. It is used as an engine fuel additive to reduce emissions of carbon monoxide and soot.
Chemical ID: MESH:C098546
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects response to substanceEXP 6480464CTDALDH2 protein affects the susceptibility to ethyl tert-butyl ether

PMID:22102104, PMID:24448831
decreases response to substanceEXP 6480464CTDALDH2 results in decreased susceptibility to ethyl tert-butyl ether

PMID:23810710
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.