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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737487
Species: Homo sapiens
RGD Object: Gene
Symbol: IFNG
Name: interferon gamma
Acc ID: CHEBI:140475
Term: MC1568
Definition: A hydroxamic acid that is N-methylpyrrole which is substituted at positions 2 and 5 by 3-(hydroxyamino)-3-oxoprop-1-en-1-yl and 3-(m-fluorophenyl)-3-oxoprop-1-en-1-yl groups, respectively. It is a potent and selective inhibitor of class II (IIa) histone deacetylase (HDAC II).
Chemical ID: MESH:C577554
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IFNGmultiple interactionsISOIfng (Mus musculus)6480464CTDMC1568 promotes the reaction [enterotoxin B, staphylococcal results in increased secretion of IFNG protein]PMID:24200994
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