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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61898
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Maoa
Name: monoamine oxidase A
Acc ID: CHEBI:1391
Term: 3,4-methylenedioxymethamphetamine
Definition: A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a 2-(methylamino)propyl group at position 5.
Chemical ID: MESH:D018817
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases activityISORGD:7357516480464CTDN-Methyl-3, 4-methylenedioxyamphetamine results in decreased activity of MAOA protein

PMID:26721607
multiple interactionsISORGD:7357516480464CTDN-Methyl-3, 4-methylenedioxyamphetamine inhibits the reaction [MAOA protein results in decreased amination of Dopamine], N-Methyl-3, 4-methylenedioxyamphetamine inhibits the reaction [MAOA protein results in decreased amination of Serotonin]

PMID:26721607
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.