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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1558619
Species: Mus musculus
RGD Object: Gene
Symbol: Ctsb
Name: cathepsin B
Acc ID: CHEBI:1391
Term: 3,4-methylenedioxymethamphetamine
Definition: A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a 2-(methylamino)propyl group at position 5.
Chemical ID: MESH:D018817
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ctsbincreases expressionISOCtsb (Rattus norvegicus)6480464CTDN-Methyl-3,4-methylenedioxyamphetamine results in increased expression of CTSB protein alternative formPMID:32186374
Ctsbmultiple interactionsISOCtsb (Rattus norvegicus)6480464CTDN-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of and results in decreased activity of CTSB proteinPMID:32186374
Ctsbmultiple interactionsISOCTSB (Homo sapiens)6480464CTDN-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of and results in decreased activity of CTSB proteinPMID:32186374
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