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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1552456
Species: Mus musculus
RGD Object: Gene
Symbol: Bak1
Name: BCL2-antagonist/killer 1
Acc ID: CHEBI:1391
Term: 3,4-methylenedioxymethamphetamine
Definition: A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a 2-(methylamino)propyl group at position 5.
Chemical ID: MESH:D018817
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bak1increases expressionISOBAK1 (Homo sapiens)6480464CTDN-Methyl-3,4-methylenedioxyamphetamine results in increased expression of BAK1 proteinPMID:23820845
Bak1multiple interactionsISOBAK1 (Homo sapiens)6480464CTD[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BAK1 proteinPMID:23820845
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