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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2275
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp3
Name: caspase 3
Acc ID: CHEBI:138935
Term: S-nitroso-L-cysteine
Definition: An L-cysteine derivative in which the sulfur atom carries a nitroso substituent. A cell-permeable low-molecular-weight nitrosothiol and nitric oxide donor.
Chemical ID: MESH:C021315
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp3multiple interactionsISORGD:7310026480464CTDS-nitrosocysteine inhibits the reaction [SIRT1 protein results in decreased cleavage of CASP3 protein]

PMID:24451382
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