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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1346271
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP21A2
Name: cytochrome P450 family 21 subfamily A member 2
Acc ID: CHEBI:138861
Term: HT-2 toxin
Definition: A trichothecene mycotoxin that is T-2 toxin in which the acetyloxy group at position 4S has been hydrolysed to the corresponding hydroxy group. It is the major metabolite of T-2 toxin.
Chemical ID: MESH:C012351
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP21A2increases expressionEXP 6480464CTDHT-2 toxin results in increased expression of CYP21A2 mRNAPMID:22982764
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