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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734103
Species: Homo sapiens
RGD Object: Gene
Symbol: NR1H4
Name: nuclear receptor subfamily 1 group H member 4
Acc ID: CHEBI:135849
Term: manidipine
Definition: null
Chemical ID: MESH:C054218
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NR1H4increases activityEXP 6480464CTDmanidipine results in increased activity of NR1H4 proteinPMID:25257666
NR1H4multiple interactionsEXP 6480464CTDmanidipine inhibits the reaction [Chenodeoxycholic Acid results in increased activity of NR1H4 protein]; manidipine inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein]PMID:25257666
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