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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61800
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Htr2a
Name: 5-hydroxytryptamine receptor 2A
Acc ID: CHEBI:135697
Term: sarpogrelate
Definition: null
Chemical ID: MESH:C064294
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Htr2aaffects bindingEXP 6480464CTDsarpogrelate binds to HTR2A protein sarpogrelate metabolite binds to HTR2A protein

PMID:8937629
Htr2aaffects bindingISORGD:7341076480464CTDsarpogrelate binds to HTR2A protein

PMID:16974069
Htr2amultiple interactionsISORGD:7341076480464CTDsarpogrelate binds to and results in decreased activity of HTR2A protein sarpogrelate binds to and results in decreased activity of HTR2A protein mutant form sarpogrelate metabolite binds to and results in decreased activity of HTR2A protein

PMID:17031071 PMID:19672037
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