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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3748
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Serpine2
Name: serpin family E member 2
Acc ID: CHEBI:135697
Term: sarpogrelate
Definition: null
Chemical ID: MESH:C064294
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Serpine2decreases expressionISORGD:700776480464CTDsarpogrelate results in decreased expression of SERPINE2 mRNA

PMID:24107419
Serpine2multiple interactionsISORGD:700776480464CTDsarpogrelate inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SERPINE2 protein] sarpogrelate inhibits the reaction [[TGFB1 protein co-treated with Serotonin] results in increased expression of SERPINE2 mRNA] sarpogrelate inhibits the reaction [[TGFB1 protein co-treated with Serotonin] results in increased secretion of SERPINE2 protein]

PMID:24107419 PMID:27097221
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