Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1310890
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptgir
Name: prostaglandin I2 receptor
Acc ID: CHEBI:135578
Term: cicaprost
Definition: null
Chemical ID: MESH:C043867
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptgiraffects localizationISOPTGIR (Homo sapiens)6480464CTDcicaprost affects the localization of PTGIR proteinPMID:11895442
Ptgirmultiple interactionsISOPTGIR (Homo sapiens)6480464CTD[cicaprost results in increased activity of PTGIR protein] which results in increased abundance of Calcium; [cicaprost results in increased activity of PTGIR protein] which results in increased abundance of Cyclic AMP; cicaprost promotes the reaction [PTGIR protein binds to GNAQ protein]; cicaprost promotes the reaction [PTGIR protein binds to GNAS protein]; GNAS protein promotes the reaction [[cicaprost results in increased activity of PTGIR protein] which results in increased abundance of Cyclic AMP]PMID:11895442
Go Back to source page   Continue to Ontology report