Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	737013
Species:	Homo sapiens
RGD Object:	Gene
Symbol:	TLR4
Name:	toll like receptor 4

Acc ID:	CHEBI:135483
Term:	pipoxolan
Definition:	null
Chemical ID:	MESH:C000121

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
TLR4	multiple interactions	ISO	Tlr4 (Mus musculus)	6480464	CTD	pipoxolan inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TLR4 protein]	PMID:32677756

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.