GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | ABCB11 | multiple interactions | ISO | Abcb11 (Rattus norvegicus) | 15036816 | RGD | Z-guggulsterone reverses the reaction [Dihydroartemisinin inhibits the reaction [ethanol decreases expression of Abcb11 protein in liver]] | | ABCB11 | increases expression | EXP | | 6480464 | CTD | pregna-4,17-diene-3,16-dione results in increased expression of ABCB11 mRNA | PMID:12525500 | ABCB11 | multiple interactions | EXP | | 6480464 | CTD | [pregna-4,17-diene-3,16-dione co-treated with Chenodeoxycholic Acid] results in increased expression of ABCB11 mRNA; [pregna-4,17-diene-3,16-dione co-treated with GW 4064] results in increased expression of ABCB11 mRNA; pregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate results in increased expression of ABCB11 protein]; pregna-4,17-diene-3,16-dione inhibits the reaction [Bile Acids and Salts results in increased expression of ABCB11 mRNA]; pregna-4,17-diene-3,16-dione inhibits the reaction [GW 4064 results in increased expression of ABCB11 mRNA]; pregna-4,17-diene-3,16-dione inhibits the reaction [NR1H4 protein results in increased expression of ABCB11 mRNA] | PMID:12525500 PMID:12705905 PMID:34767876 PMID:35523117 | ABCB11 | multiple interactions | ISO | Abcb11 (Mus musculus) | 6480464 | CTD | pregna-4,17-diene-3,16-dione inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of ABCB11 mRNA]; pregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCB11 mRNA]]; pregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCB11 mRNA]]; pregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate results in increased expression of ABCB11 mRNA]; pregna-4,17-diene-3,16-dione inhibits the reaction [yangonin promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCB11 mRNA]]; pregna-4,17-diene-3,16-dione promotes the reaction [Ethinyl Estradiol results in decreased expression of ABCB11 mRNA] | PMID:25278094 PMID:25655198 PMID:26040663 PMID:29660435 | | ||||||||||||||||||||||
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