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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1551988
Species: Mus musculus
RGD Object: Gene
Symbol: Parp1
Name: poly (ADP-ribose) polymerase family, member 1
Acc ID: CHEBI:135014
Term: erdosteine
Definition: null
Chemical ID: MESH:C048498
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Parp1multiple interactionsEXP 6480464CTDerdosteine inhibits the reaction [Cisplatin results in increased cleavage of PARP1 protein]PMID:26193055
Parp1multiple interactionsISOParp1 (Rattus norvegicus)6480464CTDerdosteine affects the reaction [Isoproterenol results in increased expression of PARP1 protein]PMID:33210414
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