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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621195
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptgr1
Name: prostaglandin reductase 1
Acc ID: CHEBI:134499
Term: 13,14-dihydro-15-oxoprostaglandin E1
Definition: A prostaglandin E obtained by formal oxidation of the 15-hydroxy group and hydrogenation of the 13,14-double bond of prostaglandin E1.
Chemical ID: MESH:C036808
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptgr1increases abundanceISOPTGR1 (Homo sapiens)6480464CTDPTGR1 protein results in increased abundance of 13,14-dihydro-15-ketoprostaglandin E1PMID:25619643
Ptgr1multiple interactionsISOPTGR1 (Homo sapiens)6480464CTD[PTGR1 protein results in increased metabolism of 15-ketoprostaglandin E] which results in increased abundance of 13,14-dihydro-15-ketoprostaglandin E1PMID:25619643
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