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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2083
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Alad
Name: aminolevulinate dehydratase
Acc ID: CHEBI:134126
Term: picrotoxin
Definition: A mixture consisting of equimolar amounts of picrotoxinin and picrotin found in the climbing plant Anamirta cocculus.
Chemical ID: MESH:D010852
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aladdecreases activityISOAlad (Mus musculus)6480464CTDPicrotoxin results in decreased activity of ALAD proteinPMID:25490531
Aladmultiple interactionsISOAlad (Mus musculus)6480464CTDcarvacryl acetate inhibits the reaction [Picrotoxin results in decreased activity of ALAD protein]PMID:25490531
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