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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620945
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp8
Name: caspase 8
Acc ID: CHEBI:133663
Term: thymol sulfate(1-)
Definition: A phenyl sulfate oxoanion that is the conjugate base of thymol sulfate, obtained by deprotonation of the sulfate group; major species at pH 7.3.
Chemical ID: MESH:D013943
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp8multiple interactionsEXP 6480464CTDThymol inhibits the reaction [Isoproterenol results in increased expression of CASP8 mRNA]

PMID:26996544
Casp8increases activityISORGD:7308466480464CTDThymol results in increased activity of CASP8 protein

PMID:21640085
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.