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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10289
Species: Mus musculus
RGD Object: Gene
Symbol: Casp3
Name: caspase 3
Acc ID: CHEBI:133663
Term: thymol sulfate(1-)
Definition: A phenyl sulfate oxoanion that is the conjugate base of thymol sulfate, obtained by deprotonation of the sulfate group; major species at pH 7.3.
Chemical ID: MESH:D013943
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp3increases activityISOCASP3 (Homo sapiens)6480464CTDThymol results in increased activity of CASP3 proteinPMID:21640085
Casp3multiple interactionsISOCasp3 (Rattus norvegicus)6480464CTDThymol inhibits the reaction [imidacloprid results in increased expression of CASP3 mRNA]; Thymol inhibits the reaction [imidacloprid results in increased expression of CASP3 protein]PMID:34171690
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