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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1344192
Species: Homo sapiens
RGD Object: Gene
Symbol: TNF
Name: tumor necrosis factor
Acc ID: CHEBI:133354
Term: bentonite
Definition: An aluminosilicate mineral consisting mostly of montmorillonite. The different types of bentonite (aluminium bentonite; calcium bentonite; potassium bentonite; sodium bentonite) are named after their dominant element.
Chemical ID: MESH:D001546
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TNFincreases expressionISOTnf (Rattus norvegicus)6480464CTDBentonite results in increased expression of TNF proteinPMID:26115597
TNFmultiple interactionsISOTnf (Rattus norvegicus)6480464CTDBentonite inhibits the reaction [deoxynivalenol results in increased expression of TNF mRNA]; Bentonite inhibits the reaction [deoxynivalenol results in increased expression of TNF protein]PMID:26115597
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