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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732480
Species: Homo sapiens
RGD Object: Gene
Symbol: HSPB1
Name: heat shock protein family B (small) member 1
Acc ID: CHEBI:133151
Term: methyl beta-cyclodextrin
Definition: A carbohydrate derivative that is beta-cyclodextrin in which some of the hydroxy groups have been methylated.
Chemical ID: MESH:C108732
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HSPB1decreases expressionISOHspb1 (Mus musculus)6480464CTDmethyl-beta-cyclodextrin results in decreased expression of HSPB1 proteinPMID:24140437
HSPB1multiple interactionsISOHspb1 (Mus musculus)6480464CTDmethyl-beta-cyclodextrin inhibits the reaction [10-nitro-oleic acid results in increased expression of HSPB1 protein]; methyl-beta-cyclodextrin inhibits the reaction [2-chloroethyl ethyl sulfide results in increased expression of HSPB1 protein]PMID:21457723 PMID:24140437
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