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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70499
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Birc5
Name: baculoviral IAP repeat-containing 5
Acc ID: CHEBI:133021
Term: venetoclax
Definition: A member of the class of pyrrolopyridines that is a potent inhibitor of the antiapoptotic protein B-cell lymphoma 2. It is used for treamtment of chronic lymphocytic leukemia with 17p deletion.
Chemical ID: MESH:C579720
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Birc5multiple interactionsISORGD:7374826480464CTD[YM 155 co-treated with venetoclax] results in decreased expression of BIRC5 protein

PMID:31837377
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