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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2325530
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mir224
Name: microRNA 224
Acc ID: CHEBI:132974
Term: C646
Definition: A pyrazolone that is 5-methyl-4-methylene-2-(p-carboxyphenyl)-2,4-dihydro-3H-pyrazol-3-one in which the exocyclic carbon of the methylene group is attached to a 5-(4,5-dimethyl-2-nitrophenyl)furan-2-yl group by a single bond. C646 is a potent, cell permeable and selective competitive inhibitor of p300 and CBP (p300/CBP) histone acetyltransferases.
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mir224decreases expressionISO 18182922RGDC646 decreased expression of miR244 in a human hepatocellular carcinoma cell line 
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