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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1305278
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Adam33
Name: ADAM metallopeptidase domain 33
Acc ID: CHEBI:132611
Term: mono(5-carboxy-2-ethylpentyl) phthalate
Definition: A phthalic acid monoester resulting from the formal condensation of one of the carboxy gruops of phthalic acid with the hydroxy group of 5-(hydroxymethyl)heptanoic acid. It is a urinary metabolite of diethylhexyl phthalate.
Chemical ID: MESH:C051450
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Adam33multiple interactionsISORGD:13132126480464CTD[[Endocrine Disruptors results in increased abundance of 2-ethyl-5-carboxypentyl phthalate] which results in increased methylation of ADAM33 intron] which results in increased expression of ADAM33 mRNAPMID:30226539
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