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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735727
Species: Homo sapiens
RGD Object: Gene
Symbol: PLAU
Name: plasminogen activator, urokinase
Acc ID: CHEBI:132238
Term: iron(III) nitrilotriacetate
Definition: An iron chelate resulting from the combination of equimolar amounts of iron(3+) and nitrilotriacetate(3-).
Chemical ID: MESH:C020326
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PLAUincreases activityEXP 6480464CTDferric nitrilotriacetate results in increased activity of PLAU mRNAPMID:17571974
PLAUincreases expressionEXP 6480464CTDferric nitrilotriacetate results in increased expression of PLAU mRNAPMID:17571974
PLAUmultiple interactionsEXP 6480464CTDDeferoxamine inhibits the reaction [ferric nitrilotriacetate results in increased activity of PLAU mRNA]; Deferoxamine inhibits the reaction [ferric nitrilotriacetate results in increased expression of PLAU mRNA]PMID:17571974
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