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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3046
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk3
Name: mitogen activated protein kinase 3
Acc ID: CHEBI:132098
Term: methoxyacetic acid
Definition: A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is replaced by a methoxy group.
Chemical ID: MESH:C013598
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk3increases phosphorylationISOMAPK3 (Homo sapiens)6480464CTDmethoxyacetic acid results in increased phosphorylation of MAPK3 proteinPMID:15103026 PMID:18486176
Mapk3multiple interactionsISOMAPK3 (Homo sapiens)6480464CTDU 0126 inhibits the reaction [methoxyacetic acid results in increased phosphorylation of MAPK3 protein]PMID:18486176
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