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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732095
Species: Mus musculus
RGD Object: Gene
Symbol: Pcna
Name: proliferating cell nuclear antigen
Acc ID: CHEBI:131518
Term: N,N-bis(2-hydroxypropyl)nitrosamine
Definition: A nitrosamine that is dipropylamine in which the hydrogen attached to the nitrogen has been replaced by a nitroso group. It is a genotoxic carcinogen, targeting the lung, liver, thyroid, and kidney.
Chemical ID: MESH:C012457
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pcnamultiple interactionsISOPcna (Rattus norvegicus)6480464CTD[Potassium Iodide co-treated with diisopropanolnitrosamine] results in increased expression of PCNA proteinPMID:29050248
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