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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619707
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptgdr
Name: prostaglandin D2 receptor
Acc ID: CHEBI:131502
Term: 7-[3-(3-cyclohexyl-3-hydroxypropyl)-2,5-dioxoimidazolidin-4-yl]heptanoic acid
Definition: A imidazolidine-2,4-dione that is 7-(2,5-dioxoimidazolidin-4-yl)heptanoic acid in which the imidazoline ring as substituted at position 3 by a 3-(3-cyclohexyl-3-hydroxypropyl) group.
Chemical ID: MESH:C030669
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptgdrmultiple interactionsEXP 6480464CTDBW 245C binds to and results in increased activity of PTGDR protein

PMID:15528449
Ptgdrmultiple interactionsISORGD:13492486480464CTDBW 245C binds to and results in increased activity of PTGDR protein, BW 245C inhibits the reaction [Prostaglandin D2 binds to PTGDR protein]

PMID:9579725
Ptgdrmultiple interactionsISORGD:15510316480464CTDBW 245C binds to and results in increased activity of PTGDR protein

PMID:20719937
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.