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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620307
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pdpk1
Name: 3-phosphoinositide dependent protein kinase-1
Acc ID: CHEBI:131196
Term: OSU-03012
Definition: A member of the class of pyrazoles that is N-[4-(pyrazol-1-yl)phenyl]glycinamide in which the pyrazole ring is substituted at positions 3 and 5 by trifluoromethyl and phenanthrene-2-yl groups respectively.
Chemical ID: MESH:C500894
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pdpk1decreases response to substanceISOPDPK1 (Homo sapiens)6480464CTDPDPK1 protein modified form results in decreased susceptibility to OSU 03012PMID:15205346
Pdpk1multiple interactionsISOPDPK1 (Homo sapiens)6480464CTDOSU 03012 binds to and results in decreased activity of PDPK1 proteinPMID:15205346
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