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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735341
Species: Homo sapiens
RGD Object: Gene
Symbol: CDKN1A
Name: cyclin dependent kinase inhibitor 1A
Acc ID: CHEBI:131194
Term: 3,3',5,5'-tetraiodothyroacetic acid
Definition: A monocarboxylic acid that is thyroacetic acid carrying four iodo substituents at positions 3, 3', 5 and 5'.
Chemical ID: MESH:C011126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CDKN1Adecreases expressionEXP 6480464CTDtetraiodothyroacetic acid results in decreased expression of CDKN1A mRNAPMID:35151786
CDKN1Aincreases expressionEXP 6480464CTDtetraiodothyroacetic acid results in increased expression of CDKN1A mRNAPMID:35151786
CDKN1Amultiple interactionsEXP 6480464CTDheteronemin inhibits the reaction [tetraiodothyroacetic acid results in decreased expression of CDKN1A mRNA]; heteronemin inhibits the reaction [tetraiodothyroacetic acid results in increased expression of CDKN1A mRNA]; tetraiodothyroacetic acid inhibits the reaction [heteronemin affects the expression of CDKN1A mRNA]; tetraiodothyroacetic acid inhibits the reaction [heteronemin results in decreased expression of CDKN1A mRNA]PMID:35151786
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