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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10802
Species: Mus musculus
RGD Object: Gene
Symbol: Il6
Name: interleukin 6
Acc ID: CHEBI:125498
Term: 1,2,3,4-tetrahydroisoquinoline
Definition: An isoquinoline that has formula C9H11N.
Chemical ID: MESH:C014843
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il6decreases expressionISOIl6 (Rattus norvegicus)6480464CTD1,2,3,4-tetrahydroisoquinoline results in decreased expression of IL6 mRNAPMID:14737019
Il6decreases response to substanceISOIL6 (Homo sapiens)6480464CTDIL6 protein results in decreased susceptibility to 1,2,3,4-tetrahydroisoquinolinePMID:14737019
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