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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621803
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hsd17b2
Name: hydroxysteroid (17-beta) dehydrogenase 2
Acc ID: CHEBI:1189
Term: 2-methoxyestrone
Definition: A 17-oxo steroid that is estrone in which the hydrogen at position 2 has been replaced by a methoxy group.
Chemical ID: MESH:C003655
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hsd17b2multiple interactionsISOHSD17B2 (Homo sapiens)6480464CTD[HSD17B2 protein results in increased metabolism of and results in decreased activity of 2-methoxyestradiol] which results in increased chemical synthesis of 2-methoxyestronePMID:16397246
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