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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737488
Species: Mus musculus
RGD Object: Gene
Symbol: Ifng
Name: interferon gamma
Acc ID: CHEBI:116509
Term: diuron
Definition: A member of the class of 3-(3,4-substituted-phenyl)-1,1-dimethylureas that is urea in which both of the hydrogens attached to one nitrogen are substituted by methyl groups, and one of the hydrogens attached to the other nitrogen is substituted by a 3,4-dichlorophenyl group.
Chemical ID: MESH:D004237
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ifngdecreases expressionISOIFNG (Homo sapiens)6480464CTDDiuron results in decreased expression of IFNG mRNA; Diuron results in decreased expression of IFNG proteinPMID:10883730 PMID:35967413
Ifngdecreases secretionISOIFNG (Homo sapiens)6480464CTDDiuron results in decreased secretion of IFNG proteinPMID:35967413
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