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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1343432
Species: Homo sapiens
RGD Object: Gene
Symbol: SERPINB2
Name: serpin family B member 2
Acc ID: CHEBI:116509
Term: diuron
Definition: A member of the class of 3-(3,4-substituted-phenyl)-1,1-dimethylureas that is urea in which both of the hydrogens attached to one nitrogen are substituted by methyl groups, and one of the hydrogens attached to the other nitrogen is substituted by a 3,4-dichlorophenyl group.
Chemical ID: MESH:D004237
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SERPINB2increases expressionEXP 6480464CTDDiuron metabolite results in increased expression of SERPINB2 mRNAPMID:24172598
SERPINB2decreases expressionISOSerpinb2 (Rattus norvegicus)6480464CTDDiuron metabolite results in decreased expression of SERPINB2 mRNAPMID:24172598
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