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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1306276
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nedd9
Name: neural precursor cell expressed, developmentally down-regulated 9
Acc ID: CHEBI:116509
Term: diuron
Definition: A member of the class of 3-(3,4-substituted-phenyl)-1,1-dimethylureas that is urea in which both of the hydrogens attached to one nitrogen are substituted by methyl groups, and one of the hydrogens attached to the other nitrogen is substituted by a 3,4-dichlorophenyl group.
Chemical ID: MESH:D004237
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nedd9increases expressionEXP 6480464CTDDiuron metabolite results in increased expression of NEDD9 mRNAPMID:24172598
Nedd9decreases expressionISONEDD9 (Homo sapiens)6480464CTDDiuron metabolite results in decreased expression of NEDD9 mRNA; Diuron results in decreased expression of NEDD9 mRNAPMID:24172598 PMID:35967413
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