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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10198
Species: Mus musculus
RGD Object: Gene
Symbol: Atf3
Name: activating transcription factor 3
Acc ID: CHEBI:116509
Term: diuron
Definition: A member of the class of 3-(3,4-substituted-phenyl)-1,1-dimethylureas that is urea in which both of the hydrogens attached to one nitrogen are substituted by methyl groups, and one of the hydrogens attached to the other nitrogen is substituted by a 3,4-dichlorophenyl group.
Chemical ID: MESH:D004237
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Atf3decreases expressionISOATF3 (Homo sapiens)6480464CTDDiuron metabolite results in decreased expression of ATF3 mRNAPMID:24172598
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